Pathophysiological justification of age- and gender-dependent morphological changes in the adipose tissue in rat models of metabolic syndrome

Introduction: The mechanisms of metabolic syndrome (MS) is one the urgent issues in medicine. Regional distribution adipose tissue should be diagnosed at clinical examination, as morphometric parameters cells active components may indicate state. Aim: aim study was to evaluate differences morphological and histological associated with development MS animals different ages gender. Material methods: An experimental carried out on 144 WAG/G Sto white rats, divided into three groups. Group 1 included young immature 3 months old; group 2 consisted 48 sexually mature aged 5–6 months; old 18 old. Each subgroups, control experimental, additionally according Results discussion: body mass indices specific weights mesenteric, epididymal, retroperitoneal subcutaneous were determined well characteristics adipocytes tissue. It shown that changes age- gender-dependent, obesity chronic inflammation Conclusions: results can used for further determination possible age gender involvement inflammation, monitoring correction dysfunction MS.